For invasive lobular breast cancer


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Several histological subtypes exist, with reports of different prognosis. The aim was to present the incidence of ILC in DBCG fromand evaluate tumours regarding diagnosis, histological subtype and grade, and relate to prognosis. The impact of histological malignancy grade on disease-free survival and overall survival was analysed using a multivariate analysis adjusting for tumour size, hormone receptor status, axillary lymph node status and patient age. The majority of the grade III tumours were among the non-classical subtypes, showing a statistically significant worse disease-free and overall survival compared to grade II, regardless of type.

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Lobular breast cancer: incidence and genetic and non-genetic risk factors

An important part of diagnosing breast cancer is staging. Staging is the process of finding out how much cancer there is and where it is located. This information is used to plan cancer treatment and develop a prognosis. Staging is a way to make sure you get the best possible treatment.

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Common breast cancer types

Invasive lobular carcinoma is a type of breast cancer that begins in the milk-producing glands lobules of the breast. Invasive cancer means the cancer cells have broken out of the lobule where they began and have the potential to spread to the lymph nodes and other areas of the body. Invasive lobular carcinoma makes up a small portion of all breast cancers.

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We recommend that you read it along with our booklet Understanding Cancer of the Breast, which you can download here pdf, 2. Breast tissue is made up of milk lobules and milk ducts where milk is made and carried to the nipple during breastfeeding. Invasive lobular breast cancer happens when cancer cells start to grow within the lobules and spread into the surrounding tissue.